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Common Questions

About CHANTIX

What is CHANTIX?

CHANTIX® (varenicline) is a prescription medicine to help adults 18 and over stop smoking. CHANTIX helps reduce the urge to smoke.

How is CHANTIX different from other smoking cessation products?

CHANTIX is a non-nicotine pill. CHANTIX targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them.

Learn more about how CHANTIX works.

What should I tell my doctor before starting CHANTIX?

Tell your doctor about all your medical conditions including if you:

  • Have ever had depression or other mental health problems, as these symptoms may worsen while taking CHANTIX.
  • Experienced nicotine withdrawal symptoms with prior quit attempts, with or without CHANTIX. Quitting smoking, with or without CHANTIX, can result in nicotine withdrawal symptoms (such as depressed mood, agitation) or a worsening of existing mental health problems, such as depression.
  • Have kidney problems or get kidney dialysis. Your doctor may prescribe a lower dose of CHANTIX for you.
  • Have a history of heart or blood vessel problems before starting CHANTIX. If you have new or worse heart or blood vessel symptoms during treatment, tell your doctor. Get emergency medical help right away if you have any symptoms of a heart attack or stroke.
  • Are pregnant or plan to become pregnant. CHANTIX has not been studied in pregnant women. It is not known if CHANTIX will harm your unborn baby. It is best to stop smoking before you get pregnant.
  • Are breastfeeding. Although it was not studied, CHANTIX may pass into breast milk. You and your doctor should discuss alternative ways to feed your baby if you take CHANTIX.

Tell your doctor about all your other medicines including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially, tell your doctor if you take:

  • Insulin
  • Asthma medicines
  • Blood thinners

When you stop smoking, there may be a change in how these and other medicines work for you.

You should not use CHANTIX while using other treatments to quit smoking. Tell your doctor if you use other treatments to quit smoking.

Know the medicines you take. Keep a list of them with you to show your doctor and pharmacist.

How do I take CHANTIX?

  1. Choose a Quit Date when you will stop smoking.
  2. Start taking CHANTIX one week (7 days) before your Quit Date. This lets CHANTIX build up in your body. You can keep smoking during this time. Make sure that you try and stop smoking on your Quit Date. If you slip up, try again. Some people need a few weeks for CHANTIX to work best.
  3. Take CHANTIX after eating and with a full glass (8 ounces) of water.
  4. It is recommended to take CHANTIX for a full 12 weeks. If you have completely quit smoking by 12 weeks, ask your doctor if another 12 weeks of CHANTIX may help you stay cigarette-free.

CHANTIX comes as a white tablet (0.5 mg) and a blue tablet (1 mg). You start with the white tablet and then usually go to the blue tablet. See the chart below for dosing instructions.

dosage guide

  • This dosing schedule may not be right for everyone. You may need a lower dose of CHANTIX if you have kidney problems or get dialysis.
  • If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, wait. Just take your next regular dose.

What is the safety information and possible side effects of CHANTIX?

Some people have had changes in behavior, hostility, agitation, depressed mood, suicidal thoughts or actions while using CHANTIX to help them quit smoking. Some people had these symptoms when they began taking CHANTIX, and others developed them after several weeks of treatment or after stopping CHANTIX. If you, your family, or caregiver notice agitation, hostility, depression, or changes in behavior, thinking, or mood that are not typical for you, or you develop suicidal thoughts or actions, anxiety, panic, aggression, anger, mania, abnormal sensations, hallucinations, paranoia, or confusion, stop taking CHANTIX and call your doctor right away. Also tell your doctor about any history of depression or other mental health problems before taking CHANTIX, as these symptoms may worsen while taking CHANTIX.

Do not take CHANTIX if you have had a serious allergic or skin reaction to CHANTIX. Some people can have serious skin reactions while taking CHANTIX, some of which can become life-threatening. These can include rash, swelling, redness, and peeling of the skin. Some people can have allergic reactions to CHANTIX, some of which can be life-threatening and include: swelling of the face, mouth, and throat that can cause trouble breathing. If you have these symptoms or have a rash with peeling skin or blisters in your mouth, stop taking CHANTIX and get medical attention right away.

Before starting CHANTIX, tell your doctor if you have a history of heart or blood vessel problems. If you have new or worse heart or blood vessel symptoms during treatment, tell your doctor. Get emergency medical help right away if you have any symptoms of a heart attack or stroke.

Use caution driving or operating machinery until you know how CHANTIX may affect you.

In clinical trials, the most common side effects of CHANTIX include:

  • Nausea (30%)
  • Sleep problems (trouble sleeping, changes in dreaming)
  • Constipation
  • Gas
  • Vomiting

These are not all the side effects of CHANTIX. Ask your doctor or pharmacist for more information.

A side effect is a negative or positive effect related to a medicine based upon clinical studies.

Tell your doctor about these side effects that bother you or that do not go away.

What is the important safety information I should know about CHANTIX?

Some people have had changes in behavior, hostility, agitation, depressed mood, suicidal thoughts or actions while using CHANTIX to help them quit smoking. Some people had these symptoms when they began taking CHANTIX, and others developed them after several weeks of treatment or after stopping CHANTIX. If you, your family, or caregiver notice agitation, hostility, depression, or changes in behavior, thinking, or mood that are not typical for you, or you develop suicidal thoughts or actions, anxiety, panic, aggression, anger, mania, abnormal sensations, hallucinations, paranoia, or confusion, stop taking CHANTIX and call your doctor right away. Also tell your doctor about any history of depression or other mental health problems before taking CHANTIX, as these symptoms may worsen while taking CHANTIX.

Do not take CHANTIX if you have had a serious allergic or skin reaction to CHANTIX. Some people can have serious skin reactions while taking CHANTIX, some of which can become life-threatening. These can include rash, swelling, redness, and peeling of the skin. Some people can have allergic reactions to CHANTIX, some of which can be life-threatening and include: swelling of the face, mouth, and throat that can cause trouble breathing. If you have these symptoms or have a rash with peeling skin or blisters in your mouth, stop taking CHANTIX and get medical attention right away.

Before starting CHANTIX, tell your doctor if you have a history of heart or blood vessel problems. If you have new or worse heart or blood vessel symptoms during treatment, tell your doctor. Get emergency medical help right away if you have any symptoms of a heart attack or stroke.

In clinical trials, the most common side effects of CHANTIX include nausea (30%), sleep problems, constipation, gas, and/or vomiting. If you have side effects that bother you or don't go away, tell your doctor.

You may have trouble sleeping, vivid, unusual, and/or strange dreams while taking CHANTIX. Use caution driving or operating machinery until you know how CHANTIX may affect you.

CHANTIX should not be taken with other quit-smoking products. You may need a lower dose of CHANTIX if you have kidney problems or get dialysis.

Before starting CHANTIX, tell your doctor if you are pregnant, plan to become pregnant, or if you take insulin, asthma medicines, or blood thinners. Medicines like these may work differently when you quit smoking.

How long should I take CHANTIX?

It is recommended CHANTIX be taken for a full 12 weeks or as prescribed by your doctor. If you have completely quit smoking by 12 weeks, ask your doctor if another 12 weeks of CHANTIX may help you stay cigarette free.

Should I take CHANTIX on an empty stomach?

Doctors recommend you take CHANTIX with food and a full glass (8 ounces) of water.

What do I do if I miss a dose of CHANTIX?

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, wait. Just take your next regular dose.

What if I slip up while taking CHANTIX?

It's okay. Remember, you may choose to smoke for the first week you are on CHANTIX. Try to stop smoking completely on your Quit Date (Day 8). But if you slip up, don't give up! Some people need a few weeks for CHANTIX to work best. In studies, 44% of CHANTIX users were quit during weeks 9 to 12 of treatment (compared to 18% on sugar pill). Some people who smoked after their Quit Date were able to quit successfully.

Will my urge to smoke go away when I take CHANTIX?

You might still feel some urge to smoke. But it might be less than you'd have without CHANTIX. Remember, it's possible that you might slip up and smoke while taking CHANTIX. If you do, you can stay on CHANTIX and keep trying to quit.

Who should not take CHANTIX?

CHANTIX has not been studied in children under 18 years of age. CHANTIX is not recommended for children under 18 years of age.

Do not take CHANTIX if you are allergic to anything in it. See a complete list of ingredients below.

You should not use CHANTIX while using other treatments to quit smoking. Tell your doctor if you use other treatments to quit smoking.

What is in CHANTIX?

Active ingredient: varenicline tartrate
Inactive ingredients: microcrystalline cellulose (NF), anhydrous dibasic calcium phosphate (USP), croscarmellose sodium NF), colloidal silicon dioxide (NF), magnesium stearate (NF), Opadry® White (for 0.5 mg), Opadry® Blue (for 1 mg), and Opadry® Clear (for both 0.5 mg and 1 mg)

How should I store CHANTIX?

  • Store CHANTIX at room temperature, 59 to 86°F (15 to 30°C)
  • Safely dispose of CHANTIX that is out of date or no longer needed
  • Keep CHANTIX and all medicines out of the reach of children

About GETQUIT®

What is the GETQUIT® Plan?

GETQUIT is the support plan developed to work with CHANTIX. GETQUIT offers:

  • A 7-day pre-quit plan that provides specific topics and activities to help you prepare for your Quit Date
  • A full year of support with activities and messages to help you learn how to stay quit
  • Learn more about GETQUIT

How can I sign up for GETQUIT?

If you are already taking CHANTIX, or have a prescription, you can sign up for GETQUIT. When you fill your prescription for CHANTIX at the pharmacy, you'll receive an enrollment card inside your box of CHANTIX. Find the number on the back of the enrollment card. Or, if your prescription comes in a bottle, find the prescription number on your pill bottle. Then go to www.getquit.com or call 1-877-CHANTIX (242-6849) and follow the instructions to enroll and set up your personalized support plan. If you have lost your card or don't have one, call 1-877-CHANTIX.

Why should I join GETQUIT?

CHANTIX is proven to be effective, but it's not a magic pill. For most people, smoking can be both a physical and a behavioral challenge. That's why we also offer GETQUIT, a support plan.

GETQUIT combines smoking cessation research with key learnings from the fields of psychology and behavioral therapy to create a day-by-day plan designed to help CHANTIX users kick the smoking habit.

In general, medication used with behavioral support can give you a better chance for quitting smoking than doing it on your own.

Learn more about GETQUIT.